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BOOP

BOOP was first described as a distinct clinical entity by Epler et al (n engl j med 1985;312:152-158). In this landmark article of BOOP, they reviewed ** and described different pathological, clinical and prognostic factors associated with BOOP than classic bronciolitis obliterans. This clinicopatholgical entity in adults has subsequently been confirmed by many investigators since then.

DISEASE OF THE BRONCHIOLES*

– Acute and chronic bronchiolitis

– RSV and other viruses

– Diffuse panbronchiolitis

– Respiratory bronahiolitis

– Proliferative bronchiolitis obliterans

– Constricitve bronchiolitis

– Idiopathic
– Post infectious (viral, mycoplasma)
– Healed toxic and fume exposure
– Connective tissue disorders
– Bone marrow and heart-lung or lung transplantation
– Drug reaction(penicillamine)

– Bronchiolitis obliterans organizing pneumonia (BOOP)

– Idiopathic
– Viral-related
– Connective tissue disorders
– Focal
– Cocaine abuse
– Drug reaction (sulphonamides)
– HIVinfection
– Post Bone Marrow Transplantation
– Myelodysplastic syndrome
– Radiation therapy

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