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Page 6/Case04/01

We began treatment for presumed Mycobacterium Tuberculosis (MTB)

Isoniazid, rifampin, and pyrazinimide were initiated for presumed MTB. Prednisone was added to help decrease the size of the nodes. The family had Mantoux tests, which were all negative.


Mycobacterium avium complex: diagnosis was confirmed by cultures of the BAL and biopsy specimen


Immunodeficiency work-up: negative;
HIV: negative.
Urine for VMA and HVA normal.

The treatment for MTB was discontinued and she was started on clarithromycin, rifabutin and ciprofloxacin. After about 8 weeks of therapy with the 3-drug regimen, she developed neutropenia. The rifabutin was stopped at that time and she continued on two antibiotics for an additional month and is to be reevaluated in clinic for ongoing management.

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