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ANSWER

1) Acquisition of new bacterial pathogens like Burkholderia cepacia species, or emergence of antibiotic-resistant organisms.

2) Viral infections with the usual respiratory viral pathogens.

3) Infection with mycobacteria, typical and atypical.

4) Fungal and parasitic infections are rare causes of pulmonary exacerbations.

WHAT ABOUT THE NON-INFECTIOUS CAUSES OF DETERIORATING PULMONARY STATUS?



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