Daniel Genkin, PhD (cand)
Toronto Metropolitan University, Toronto, ON

Quantifying ventilation and perfusion abnormalities is relevant to the clinical understanding and management of patients with COPD. There exist several established computed tomography (CT)- and magnetic resonance imaging (MRI)-based methodologies that can quantify ventilation/perfusion (functional) information, but they require injected or inhaled contrast agents, ionizing radiation or expensive and specialized equipment. The purpose of this presentation is to review emerging imaging methods derived from 1Hydrogen MRI free-breathing techniques (phase resolved functional lung (PREFUL), Fourier Decomposition (FD)) that provide functional information at low cost, and therefore may be widely utilized for assessment of lung diseases.

Learning Objectives:
At the end of this presentation, attendees will be able to:

  • Summarize established and emerging CT and MRI functional imaging methods;
  • Discuss and interpret the quantitative biomarkers provided by functional lung MRI; and
  • Understand the potential role of functional lung MRI in COPD clinical understanding and management.

CanMEDS Roles Addressed: Scholar