Dr. Benjamin Smith, McGill University, Montréal ,QC

The airway tree is the gateway for inhaled particulates, both noxious and therapeutic, and variation in airway tree structure is common in the general population. Dr. Smith will present recent research suggesting that variation in airway tree structure may play a critical role in clinical susceptibility to inhaled noxious particulates and, by extension, inhaled pharmacotherapy efficacy. Understanding the biological basis of airway tree variation may lead to interventions that promote resilient lung development and maintenance across the lifespan.

Learning Objectives
At the end of this presentation, attendees will be able to:

  • Provide an evolutionary perspective on human airway tree structure;
  • Describe variation in native airway tree structure in the general population; and
  • Relate this variation in airway structure to chronic obstructive lung disease susceptibility.

CanMEDs Competencies addressed:
Collaborator, Medical Expert