Dennis Jensen, PhD
McGill University, Montreal, QC

First, this presentation will present evidence on the role of pathophysiological abnormalities in pulmonary gas exchange efficiency and respiratory mechanics in the etiology of exertional dyspnea and exercise intolerance in people with chronic obstructive pulmonary disease (COPD). Second, this presentation will discuss how these pathophysiological abnormalities are targeted by therapies to alleviate exertional dyspnea and improve exercise tolerance in people with COPD.

Learning Objectives:
At the end of this presentation, attendees will be able to:

  • Explain the importance of pulmonary gas exchange inefficiency to exertional dyspnea in COPD;
  • Explain the importance of critical inspiratory constraints on exertional dyspnea in COPD; and
  • Explain the physiological mechanisms underlying exertional dyspnea relief with common therapeutic approaches in COPD.

CanMEDS Roles Addressed: Collaborator, Communicator, Health Advocate, Leader, Medical Expert, Professional, Scholar